DELHI: Exercise is a cornerstone in the management of metabolic dysfunction-associated steatotic liver disease (MASLD), according to a study led by an Indian-origin researcher. MASLD, previously known as non-alcoholic fatty liver disease (NAFLD). Obesity is a chronic liver disease that occurs when fat accumulates in the liver of people who do not drink much alcohol. It may affect people with diabetes, obesity, high blood pressure or high cholesterol.
The study, led by Hirsch D. Trivedi and team at Cedars-Sinai Medical Center in California, US, showed that exercise may also be beneficial for patients who have progressed to cirrhosis – severe scarring of the liver. In addition to weight loss, exercise can help reduce liver fat, improve inflammation biomarkers and boost heart health, a study published in the International Journal of Liver found. “Individualized exercise regimens should be prioritized for all patients, including those receiving pharmacotherapy,” the researchers said in the paper.
Jonathan G., a member of the research team in the Department of Medicine at Cedars-Sinai. “Exercise is a great therapeutic tool in all stages of liver disease, including advanced liver disease! Physical activity will not be limited based solely on the stage of liver disease and “Even people with cirrhosis can exercise safely and effectively.” Findings based on a review of several pre-clinical and clinical studies suggest that increased physical activity, primarily exercise, is associated with reduced incidence of liver disease and improved outcomes. The team also urged the adoption of an evidence-based, systematic approach to prescribing exercise for MASLD patients. “Exercise will remain an essential intervention for the management of steatotic liver disease, with most of the evidence supporting its benefits in MASLD. Regular physical activity improves insulin sensitivity, reduces liver fat accumulation, and reduces liver inflammation. Reduces the biomarkers,” the team called for more research to refine the exercise protocol.
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