What are HPLC Analysers? Doctors say they could be key to accurate diabetes diagnosis

New Delhi: Diabetes screening is essential for early detection and management of this chronic condition, which affects millions worldwide. An alarming rise in diabetes prevalence is apparent, driven by lifestyle changes, sedentary behavior, and dietary habits. Early diagnosis is crucial, as uncontrolled diabetes can lead to severe complications like cardiovascular disease, kidney damage, and neuropathy. Timely identification of prediabetes or diabetes allows doctors to implement lifestyle changes and treatments to slow disease progression and improve patients’ quality of life.

While talking about HPLC anaylsers, Dr.Shrey Srivastava, Senior Consultant of Internal medicine at Sharda Hospital, said, “High-Performance Liquid Chromatography (HPLC) analyzers play a major role in diabetes screening and diagnosis, offering precision and reliability in measuring glycated hemoglobin (HbA1c) levels. The HbA1c test is critical in diabetes care, as it provides an average blood glucose level over the past two to three months, a key indicator for diabetes diagnosis and management.”

HPLC analysers operate by separating blood sample components based on their interactions with a stationary phase within a column. As the sample moves through the column, distinct compounds elute at different times, allowing precise detection and quantification. This mechanism enables HPLC to measure HbA1c levels with exceptional accuracy, reducing the risk of false-positive or false-negative results. By indicative HbA1c more reliably than other methods, HPLC minimizes diagnostic errors and supports confident clinical decisions.

In diabetes care, HPLC analysers offer benefits beyond initial screening. They play a critical role in ongoing disease management by regularly assessing HbA1c levels, which guide treatment adjustments. For instance, an elevated HbA1c result signals the need for medication changes or lifestyle interventions. Additionally, HPLC provides stability and consistency, making it a preferred choice in clinical labs where accurate, reproducible results are essential for patient safety and treatment planning.

HPLC analysers support accurate diabetes diagnosis and improve patient care by enabling precise HbA1c measurements. This technology is now widely used for diabetes check-ups and has become the choice of many laboratories.

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