Will Ismael Saibari start for his Bundesliga debut or will Nathaniel Brown continue at No.10 for Bayern Munich on the opening night of the season at home to VfB Stuttgart?
Follow build-up and live coverage of every match here!
See who’s in and who’s set to miss out on Matchday 1…
*kick-off at 3.30pm CEST unless stated
Friday 28 August
Bayern Munich vs. VfB Stuttgart (8.30pm CEST)
Bayern: Neuer (c) – Laimer, Tah, Kim, Stanišić – Kimmich, Pavlović – Olise, Brown, Díaz – Kane
Out: Gnabry (groin), Musiala (fitness)
Doubtful: Karl (hamstring)
Coach: Vincent Kompany
Stuttgart: Bredlow – Vagnoman, Jeltsch, Chabot, Mittelstädt – Prömel, Stiller – El Khannouss, Undav (c), Tomás – Pejčinović
Out: Arévalo (back), Assignon (shoulder), Diehl (thigh), Jaquez (muscular), Nartey (hamstring), Seimen (hamstring), Zagadou (hamstring)
Doubtful: Führich (muscular)
Coach: Sebastian Hoeness
Saturday 29 August
RB Leipzig vs. Borussia Mönchengladbach
Leipzig: Vandevoordt – Baku, Orbán, Castello, Room (c) – Gruda, Seiwald, Banzuzi – Bakayoko, Gomis, Nusa
Out: Baumgartner (thigh), Gebel (knee), Klostermann (groin), Ouédraogo (shoulder), Rômulo (knee)
Doubtful: Nyland (foot)
Coach: Martin Demichelis
Gladbach: Nicolas – Hashioka, Itakura, Diks, Ullrich – Sander, Stöger – Mohya, Bolin, Hack – Kleindienst (c)
Out: Castrop (shoulder), Konoplya (knee)
Doubtful: One (muscular)
Coach: Eugene Polanski
Mainz vs. Paderborn
Mainz: Zentner – da Costa, Posch, Kohr – Caci, Lee, Sano, Amiri (c), Mwene – Becker, Tietz
Out: Martel (knee), Nebel (groin), Silas (broken leg)
Doubtful: Hollerbach (match fitness)
Coach: Urs Fischer
Paderborn: Noll – ter Horst, Scheller, Hansen – Curda (c), Ulrich, Castaneda, Obermair – Millgram, Marino, Vidović
Out: Awortwie-Grant (ankle), Gayret (knee), Klaas (groin), Michel (groin)
Doubtful: Eickel (back)
Coach: Ralf Kettemann
Union Berlin vs. Eintracht Frankfurt
Union: Raab – Juranović, Querfeld, Van den Bosch, Rothe – Jeong, Kemlein, Khedira (c), Burcu – Latte Lath, Ljubičić
Out: Friedrich (unconfirmed), Markgraf (knee), Nsoki (calf), Rønnow (groin), Skov (muscular)
Doubtful: Burke (Achilles), Ilić (ill)
Coach: Mauro Lustrinelli
Frankfurt: Santos – Baum, Koch (c), Otávio, Kosugi – Amaimouni-Echghouyab, Götze, Onyedika, Uzun – Ebnoutalib, Burkardt
Out: Collins (back), Ngankam (hamstring)
Doubtful: Aseko (knee), Dōan (muscular), Larsson (muscular)
Coach: Adi Hütter
Cologne vs. Hoffenheim
Cologne: Schwäbe (c) – Castro-Montes, Simpson-Pusey, Lochoshvili, Mensah – Jóhannesson, Skhiri – Maina, Bülter, El Mala – Ache
Out: Hübers (knee), Sebulonsen (hamstring)
Doubtful: Waldschmidt (muscular)
Coach: René Wagner
Hoffenheim: Baumann (c) – Coufal, Kabak, Hajdari, Rots – De Cat, Avdullahu, Burger – Daghim, Hložek, Wimmer
Out: Lemperle (suspended)
Doubtful: Bernardo (Achilles), Prass (muscle)
Coach: Christian Ilzer
Elversberg vs. Bayer Leverkusen
Elversberg: Kristof – Gyamerah, Pinckert (c), Rohr, Günther – Keidel, Poręba – Petkov, Onyeka, Campbell – Schnellbacher
Out: Seifert (ankle), Zimmerschied (back)
Doubtful: –
Coach: Vincent Wagner
Leverkusen: Flekken – Vázquez, Badé, Tapsoba (c), Gutiérrez – Fernández, García – Tella, Maza, Moreira – Schick
Out: Culbreath (foot), Eichhorn (ill)
Doubtful: Ben Seghir (hamstring), Terrier (unconfirmed)
Coach: Carles Martinez
Borussia Dortmund vs. Hamburg (6.30pm CEST)
Dortmund: Kobel – Gadou, Anton (c), Bensebaini – Ryerson, Veerman, Nmecha, Svensson – Karetsas, Konstantelias – Guirassy
Out: Can (knee), Schlotterbeck (ankle)
Doubtful: –
Coach: Niko Kovač
Hamburg: Heuer Fernandes – Capaldo (c), Bornauw, Torunarigha – Jatta, Remberg, Sambi Lokonga, Lemke – Adeline, Grønbæk – Daka
Out: Muheim (muscular), Omari (shoulder), Røssing-Lelesiit (ankle), Sahiti (muscular)
Doubtful: –
Coach: Merlin Polzin
Sunday 30 August
Freiburg vs. Werder Bremen
Freiburg: Backhaus – Treu, Ginter, Lienhart, Makengo – Eggestein, Engelhardt – Beste, Suzuki, Grifo (c) – Matanović
Out: muesli (knee)
Doubtful: Yilmaz (ill)
Coach: Julian Schuster
Bremen: Hein – Schmetgens, Pieper, Friedl (c), Deman – Stage, Lynen, Reis – Njinmah, Füllkrug, Mbangula
Out: Agu (muscular), Topp (knee), Weiser (muscular), Wójcik (calf)
Doubtful: Dinkçi (muscle)
Coach: Daniel Thioune
Augsburg vs. Schalke (5.30pm CEST)
Augsburg: Dahmen – Matsima, Gouweleeuw (c), Brackelmann – Wolf, Massengo, Rieder, Behrens – Kade, Fellhauer – Gregoritsch
Out: Mounié (match fitness)
Doubtful: Breithaupt (toe), Claude-Maurice (calf)
Coach: Manuel Baum
Schalke: Karius – T. Becker, Katić, Kuruçay – Ljubicic, Schallenberg, El-Faouzi, V. Becker – Karaman (c), Aouchiche – Sylla
Out: Gantenbein (ankle), Højlund (Achilles), Lasme (calf)
Doubtful: –
Coach: Miron Muslić