health desk : Scientists have identified a new and unique population of stem cells that serve as a master source for tendons and ligaments throughout the body. This connective tissue works to connect muscles to bones. According to this new research published in the journal 'Cell', in serious conditions like Lumbar Spinal Stenosis, these cells become unusually active. Due to this disease, the thickened ligaments reduce the space inside the spinal canal, which puts pressure on the spinal nerves and patients have to face severe pain, numbness and difficulty in walking. This problem affects approximately 103 million people worldwide.
Researchers at Weill Cornell Medicine and Hospital for Special Surgery found that these specialized stem cells reside in a specific location within tendons and ligaments, acting as a reservoir for tissue growth and repair. During the study conducted on rats, it was also revealed that by reducing calcium signaling, this abnormal growth in rats can be successfully prevented. Scientists believe that this discovery may open new possibilities for including old medicines used in the treatment of high blood pressure in its treatment in the future.
Study co-authors Dr. Matthew Greenblatt and Dr. Shravishta Iyer said that with the identification of these special stem cells, patients will no longer have to depend only on surgery, but the initial causes of the disease can be corrected mechanically. This universal stem cell has been found to be present in many parts of the body, including the kneecap ligament and Achilles tendon. These cells have been found in much higher numbers in the ligaments of patients suffering from stenosis than in normal people, which has the potential to completely change the way spinal cord treatment is done in the future.
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